Epidemiology of Sarcoidosis: New Frontiers to Explore
Epidemiology of Sarcoidosis: New Frontiers to Explore
Epidemiologic studies have been playing frontier roles to explore determinants of sarcoidosis by observing affected persons with the related population. Since 1990, more than 100 epidemiolgic papers have been added to the Medline and PubMed databases. Of them, just a few were dated after March 2001. This article is focused on the papers after that time, referring to a number of previous important epidemiologic studies. The review is arranged according to two major epidemiologic categories: (1) host-related findings such as age, sex, race, familial clustering, and lifestyle; and also (2) time- and space-related findings such as exposures, geographical variation, local clustering, climate and seasonal variation, migration, and time-space clustering (transmission).
Epidemiologic studies have been playing frontier roles to explore determinants of sarcoidosis, observing affected persons with the related population. Since 1990, more than 100 epidemiologic papers on sarcoidosis have been searched in the Medline and PubMed databases. Of them, just a few papers were dated after March 2001. This article is focused on the papers published after that time, in reference to previously accumulated important epidemiologic evidence. Various epidemiologic findings associated with sarcoidosis were documented between 1950 and 2001, as listed in Table 1 ; however, each finding is not an independent element, but reflects initiator-response factors that are complicatedly interwoven.
Epidemiologic studies have been playing frontier roles to explore determinants of sarcoidosis by observing affected persons with the related population. Since 1990, more than 100 epidemiolgic papers have been added to the Medline and PubMed databases. Of them, just a few were dated after March 2001. This article is focused on the papers after that time, referring to a number of previous important epidemiologic studies. The review is arranged according to two major epidemiologic categories: (1) host-related findings such as age, sex, race, familial clustering, and lifestyle; and also (2) time- and space-related findings such as exposures, geographical variation, local clustering, climate and seasonal variation, migration, and time-space clustering (transmission).
Epidemiologic studies have been playing frontier roles to explore determinants of sarcoidosis, observing affected persons with the related population. Since 1990, more than 100 epidemiologic papers on sarcoidosis have been searched in the Medline and PubMed databases. Of them, just a few papers were dated after March 2001. This article is focused on the papers published after that time, in reference to previously accumulated important epidemiologic evidence. Various epidemiologic findings associated with sarcoidosis were documented between 1950 and 2001, as listed in Table 1 ; however, each finding is not an independent element, but reflects initiator-response factors that are complicatedly interwoven.
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